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Noticiario genética


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Headline (Posted) Abstract
Modified experimental vaccine protects monkeys from deadly malaria (22 May 2017) Researchers have modified an experimental malaria vaccine and showed that it completely protected four of eight monkeys that received it against challenge with the virulent Plasmodium falciparum malaria parasite. In three of the remaining four monkeys, the vaccine delayed when parasites first appeared in the blood by more than 25 days.

Insects resist genetic methods to control disease spread, study finds (19 May 2017) Insects possess a naturally occurring resistance to the use of gene-editing technology to prevent diseases such as malaria, new research shows.

Engineered protein enlisted to battle the MERS virus (19 May 2017) Researchers converted a staple human ubiquitin protein into an anti-viral tool. Through subtle tweaks, they created an engineered version of the ubiquitin that binds more tightly and paralyzes a key enzyme in MERS to halt viral replication in cells. Other synthetic forms of ubiquitin can be quickly generated to target a diverse range of pathogens.

How RNA formed at the origins of life (19 May 2017) A single process for how a group of molecules called nucleotides were made on the early Earth, before life began, has been suggested by a team of researchers.

Natural resistance to malaria linked to variation in human red blood cell receptors (18 May 2017)
Researchers have discovered that protection from the most severe form of malaria is linked with natural variation in human red blood cell genes. A study has identified a genetic rearrangement of red blood cell glycophorin receptors that confers a 40 percent reduced risk from severe malaria. This opens a new avenue of research for malarial therapeut [+]

Untangling the genetic legacy of tomato domestication (18 May 2017)
Favorable mutations that went along with increased fruit size and other beneficial traits in tomato plants do not always play well together. A study published in Cell found that natural mutations in two important tomato genes that were selected for different purposes in breeding can cause extreme branching and reduce fruit yield when they occur in [+]

Cell mechanism that transforms electrical signals into chemical ones explained (18 May 2017) Freiburg scientists explain the cell mechanism that transforms electrical signals into chemical ones.

Brain blood vessel lesions tied to intestinal bacteria (18 May 2017) Bacteria in the gut can influence the structure of the brain's blood vessels, and may be responsible for producing malformations that can lead to stroke or epilepsy, new research suggests. The study adds to an emerging picture that connects intestinal microbes and disorders of the nervous system.

Tiny bubbles help heal broken bones, in pigs (17 May 2017) Researchers have developed a much needed alternative to bone grafts that could help alleviate the long-term hospitalization, disability, and considerable costs to the health system associated with non-healing fractures.

Microbes seen controlling action of host's genes (17 May 2017)
Microbes can control their animal hosts by manipulating the molecular machinery of their cells, triggering patterns of gene expression that consequently contribute to health and disease, new research shows. The work, which was conducted in zebrafish and mice cells, could have implications for human inflammatory bowel diseases like Crohn's disease a [+]

Social networking for the proteome, upgraded (17 May 2017) Researchers have mapped the interaction partners for proteins encoded by more than 5,800 genes, representing over a quarter of the human genome, according to a new study. The network, dubbed BioPlex 2.0, identifies more than 56,000 unique protein-to-protein interactions -- 87 percent of them previously unknown -- the largest such network to date.

Researchers invented tools from flashes of light for decoding and controlling signalling circuits in living cells (17 May 2017)
Researchers have invented new tools for decoding and controlling signalling circuits in living cells with flashes of light. In principle, any cellular circuit can now be targeted with the new method. By using this approach, the researchers discovered that major biological signalling circuits can be made to resonate when driven at their resonant fre [+]

New study sheds light on origins of life on Earth through molecular function (17 May 2017) Debate exists over how life began on Earth, but a new study provides evidence for a 'metabolism-first' model. Scientists have traced the origins and evolution of molecular functions through time. The study shows metabolism and binding arose first, followed by the functional activities of larger macromolecules and cellular machinery.

Macrophages identified as key factor for regeneration in mammals (16 May 2017) New findings shed light on how immune cells might be harnessed to someday help stimulate tissue regeneration in humans.

Fishing can lead to rapid evolutionary changes in exploited fish populations (16 May 2017) Cohort after cohort, fishing typically removes large fish from the population and can lead to rapid evolutionary changes in exploited fish populations.

How plants use sunlight to tell time via cell protein signaling (16 May 2017)
Researchers have solved a key mystery of how plants tell time. Researchers learned a chemical bond in the protein Zeitlupe forms and breaks in reaction to sunlight at varying rates, signaling plants when to bloom, metabolize and store energy, and other functions. The discovery means plant clocks can be tuned by targeted mutations to plant proteins [+]

Assembling life's molecular motor (15 May 2017)
As part of a project dedicated to modeling how single-celled purple bacteria turn light into food, a team of computational scientists simulated a complete ATP synthase in all-atom detail. The work builds on the project’s first phase—a 100-million atom photosynthetic organelle called a chromatophore—and gives scientists an unprecedented glimpse into [+]

Carnivorous plant's prized genetic treasures, unveiled (15 May 2017)
The carnivorous humped bladderwort plant, Utricularia gibba, is a sophisticated predator. It uses vacuum pressure to suck prey into tiny traps at speeds less than a millisecond. A new genomic analysis shows that, over millions of years, it repeatedly retained and enhanced genetic material associated with its carnivorous nature. These include genes [+]

More genes turned on when plants compete (15 May 2017) Some people travel to northern California for wine. However, one plant biologist treks to the Golden State for clover. The lessons of plant diversity and competition learned from a clover patch can potentially unlock secrets on plant interactions around the globe.

Stem cells in plants and animals behave surprisingly similarly (12 May 2017) A new study shows that the behavior of stem cells in plants and animals is surprisingly similar. The researchers were able to produce mathematical equations that reveal very small differences in the behavior of the proteins. The results can hopefully be used in stem cell research involving humans.

Immune cells rely on receptor to signal counterattack on parasitic worm (12 May 2017) Immune cells, called macrophages, may rely on a compound to signal an attack to beat back attacks from parasitic worms, according to an international team of researchers.

'Molecular prosthetics' can replace missing proteins to treat disease (11 May 2017)
Researchers have demonstrated that a small molecule can transport iron in human cells and live animals when proteins that normally do the same job are missing, a condition that often causes severe anemia in patients. Such 'molecular prosthetics' might treat a host of incurable diseases caused by protein deficiencies, such as anemias, cystic fibrosi [+]

This nasal receptor mediates the appetizing smell of fish food (11 May 2017)
The aquatic environment is full of tantalizing chemicals that can guide a fish to mates or meals. Now, scientists in Japan have identified the olfactory receptor and brain circuitry that picks up the scent of adenosine triphosphate, or ATP. Although mostly known for carrying energy within cells, ATP is also a constituent of fish prey such as brine [+]

Study of worms reveals 'selfish genes' that encode a toxin, and its antidote (11 May 2017) A worm commonly used in lab research possesses a pair of genes that encode both a poison and its antidote, scientists have discovered. The genes represent one of the clearest examples to date of a 'selfish genetic element' at the molecular level.

Disentangling chloroplast genetics (11 May 2017) Proper DNA inheritance is essential for healthy chloroplast: the energy center of all plant cells. Researchers discover a new gene in chloroplast that disentangles its DNA for proper plant health.

First comprehensive map of subcellular localization of proteins reveals new insights (11 May 2017) The first analysis of how proteins are arranged in a cell was published today in Science, revealing that a large portion of human proteins can be found in more than one location in a given cell.

Rare feline genetic disorders identified through whole genome sequencing (11 May 2017) Veterinary neurologists found a genetic link between degenerative myelopathy (DM) in dogs and amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease in people. Now they have found that a biomarker test that helps diagnose ALS also can assist with determining a diagnosis for degenerative myelopathy.

Chemical stimuli can support growing of stable cartilage cells (11 May 2017)
Cell-based therapies could offer a way to treat cartilage injuries before the ultimate damage of osteoarthritis on articular cartilage, a new study suggests. Cartilage-derived chondrocytes can be used for cartilage repair, but the expanded cells quickly lose their cartilage-specific characteristics. Researchers now show that a cytoskeleton-affectin [+]

Genome sequence of fuel-producing alga announced (10 May 2017) The genome of the fuel-producing green microalga Botryococcus braunii has been sequenced by a team of researchers. In addition to sequencing the genome, other genetic facts emerged that ultimately could help his team and others studying this green microalga further research toward producing algae and plants as a renewable fuel source.

Controlling bacteria's necessary evil (10 May 2017) Until now, scientists have only had a murky understanding of how these relationships arise. Now they have an answer. It's good news and bad news, germophobes: The bad news? Mutualistic bacteria start out by invading animal cells just like malevolent disease-causing bacteria do. The good news? Once they're in, they calm down and play nice.

Antibiotic breakthrough: How to overcome gram-negative bacterial defenses (10 May 2017) Scientists report that they now know how to build a molecular Trojan horse that can penetrate gram-negative bacteria, solving a problem that for decades has stalled the development of effective new antibiotics against these increasingly drug-resistant microbes.

Link between common brain disease and gut microbiome (10 May 2017) Bacteria in the gut microbiome drive the formation of cerebral cavernous malformations (CCMs), clusters of dilated, thin-walled blood vessels in the brain that can cause stroke and seizures. The research team's research suggests that altering the microbiome in CCM patients may be an effective therapy for this cerebrovascular disease.

Sugar or protein? How fruit fly brains control what they choose to eat (10 May 2017) Using fruit flies, researchers say they have identified a specific and very small set of brain cells -- dubbed dopamine wedge neurons -- responsible for driving the insects' food preferences toward what they need, rather than what they like.

How cells combat Salmonella (10 May 2017) With drug resistance being on the rise worldwide, bacterial infections pose one of the greatest global threats to human health. By deciphering the host-pathogen interaction on a molecular level, researchers hope to pave the way for new therapies. Studying the cell's reaction to Salmonella, scientists have now made a critical discovery.

A possible way to new antibiotics (10 May 2017) Researchers have developed a new method to shed light onto a mostly unknown process of bacterial protein production. Their results could be used for the design of new antibiotics.

A new tool to decipher evolutionary biology (09 May 2017) A new bioinformatics tool to compare genome data has been developed. The program called 'ModelFinder' uses a fast algorithm and allows previously not attainable new insights into evolution.

Cell biology: A molecular rivet for long-range force transmission (09 May 2017) Researchers have described, for the first time, how plastin, an actin-bundling protein, acts as a molecular rivet, providing global connectivity to the cortex underlying the plasma membrane of embryonic cells to facilitate polarization and cell division.

New major gene expression regulator in fungi (08 May 2017)
Changing a single letter, or base, in an organism's genetic code impact its traits. Subtler changes can and do happen: in eukaryotes, one such modification involves adding a methyl group to base 6 of adenine (6mA). Researchers report the prevalence of 6mA modifications in the earliest branches of the fungal kingdom. This little-explored realm provi [+]

The evolutionary story of the birch tree, told through 80 genomes (08 May 2017)
A new study sequences the genomes of 80 silver birch trees, a tree that has not been studied much by scientists despite its commercial value for papermaking, construction, furniture-building and more. Researchers identified genetic mutations including mutations that may affect how well birch trees grow and respond to light at different latitudes an [+]

Maternal and paternal cooperation in plants (08 May 2017) Researchers disprove the assumption that parents conflict with one another during a plant's embryonic development, explains a new report.



Noticias sobre Genética | EL PAÍS


Genética cotidiana (Prof. José Luis Micol Molina) 

Selección de noticias sobre genética aparecida en medios de comunicación español, y se añade un breve comentario. Se incluye un enlace a la noticia en español y cuando es posible, otro al artículo científico original en inglés. (Prof. José Luis Micol Molina, Catedrático de Genética, Universidad Miguel Hernández)


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Biological Sciences - Genetics: 394 journals.

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El ADN es una de las moléculas con la aparente e inquietante voluntad de extenderse en el tiempo y el espacio y la única con la capacidad de originar esos conjuntos de materia organizada que llamamos seres vivos, que curiosamente poseen la misma aparente e inquietante voluntad que la molécula que los codifica.