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Noticiario genética


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Headline (Posted) Abstract
Findings about cilia on cells of the vessel wall may be relevant for diabetes treatment (04 Dec 2020)
A new study shows that primary cilia, hair-like protrusions on endothelial cells inside vessels, play an important role in the blood supply and delivery of glucose to the insulin-producing beta cells in the pancreatic islets. The findings may be relevant for transplantation therapies in diabetes, as formation of functional blood vessels is importan [+]

New DNA modification 'signature' discovered in zebrafish (03 Dec 2020) Researchers have revealed a previously unknown DNA modification in zebrafish - one of human's distant evolutionary cousins.

3D protein modeling suggests why COVID-19 infects some animals, but not others (03 Dec 2020) Some animals are more susceptible to COVID-19 infection than others, and new research suggests this may be due to distinctive structural features of a protein found on the surface of animal cells.

What makes certain groups more vulnerable to COVID-19? (03 Dec 2020)
What makes the elderly and people with underlying conditions more vulnerable to COVID-19? According to a new study, clues can be found in the proteins involved in initiating infection, as the virus binds to host cells of different animals. Greater cellular oxidation with aging and sickness may explain why seniors and people with chronic illness get [+]

The helix of life: New study shows how 'our' RNA stably binds to artificial nucleic acids (03 Dec 2020)
Xeno nucleic acids are essential for the development of nucleic acid-based drugs. To be effective, they need to be able to stably bind to natural RNA (a cellular single-stranded version of the DNA, which is essential for all body processes). However, it is unclear how, if at all, RNA hybridizes with these xeno nucleic acids. A new study sheds light [+]

Understanding bacteria's metabolism could improve biofuel production (03 Dec 2020) A new study reveals how bacteria control the chemicals produced from consuming 'food.' The insight could lead to organisms that are more efficient at converting plants into biofuels.

What social distancing does to a fish brain (02 Dec 2020) Researchers have discovered a brain molecule that functions as a 'thermometer' for the presence of others in an animal's environment. Zebrafish 'feel' the presence of others via mechanosensation and water movements -- which turns the brain hormone on.

Visualization reveals how a protein 'hunkers down' to conserve energy (02 Dec 2020)
A visualization made from nearly 100,000 electron microscope images has revealed the ingenious way a protein involved in muscle activity shuts itself down to conserve energy. The protein is called myosin and it is known as a molecular motor because of the way it interacts with other proteins and energy molecules to generate force and movement. It i [+]

Cell membranes in super resolution (02 Dec 2020) For the first time ever, expansion microscopy allows the imaging of even the finest details of cell membranes. This offers new insights into bacterial and viral infection processes.

Molecular 'barcode' helps decide which sperm will reach an egg (01 Dec 2020) A protein called CatSper1 may act as a molecular 'barcode' that helps determine which sperm cells will make it to an egg and which are eliminated along the way.

CRISPR tagging improves accuracy of model cells grown from stem cells (01 Dec 2020) CRISPR tags are being used to identify all of the transcription factors necessary to turn a pluripotent stem cell into a suitable adult cell for research, and possible future cell therapies. An article documents its use for making adult neuronal cells, but the technique could be applied to any cell type.

Scientists discover role of protein in detecting the common cold virus (01 Dec 2020) The role of a protein in detecting the common cold virus and kickstarting an immune response to fight infection has been uncovered by a team of scientists.

Tweaking carotenoid genes helps tomatoes bring their A-game (01 Dec 2020)
Researchers led by the University of Tsukuba demonstrated that Target-AID gene editing technology can be used to simultaneously introduce single-base changes into multiple genes in tomatoes. Using this technique, the researchers altered three genes associated with carotenoid accumulation, resulting in elevated levels of carotenoids, particularly ly [+]

Chemical memory in plants affects chances of offspring survival (01 Dec 2020) Researchers have uncovered the mechanism that allows plants to pass on their 'memories' to offspring, which results in growth and developmental defects.

Plants on aspirin (01 Dec 2020)
For centuries humans were using willow barks to treat a headache or an inflamed tooth. Later, the active ingredient, the plant hormone salicylic acid, was used to develop painkillers like Aspirin. But what happens, if plants are treated with these painkillers? By doing so, scientists discovered an unexpected bioactivity of human pharmaceuticals in [+]

Bacteria in iron-deficient environments process carbon sources selectively (01 Dec 2020) Looking at a group of bacteria from soil, researchers discovered that these organisms overcome limitation in their carbon processing machinery by rerouting their metabolic pathways to favor producing iron-scavenging compounds.

New method identifies adaptive mutations in complex evolving populations (30 Nov 2020) A scientist has developed a method to study how HIV mutates to escape the immune system in multiple individuals, which could inform HIV vaccine design.

The genetic blueprint that results in foot-and-mouth being so infectious (30 Nov 2020)
Scientists have conducted a 'molecular dissection' of a part of the virus that causes foot-and-mouth disease, to try and understand why the pathogen is so infectious. A team of scientists has investigated the significance of the unusual way the virus's genome - or genetic blueprint - codes for the manufacture of a protein called 3B. The protein is [+]

Getting to the core of nuclear speckles (30 Nov 2020)
Scientists have identified the molecules that form the scaffold of nuclear speckles. The two proteins in question are SON and SRRM2, which are present in different variations throughout the entire animal kingdom. Both molecules are involved in the processing of RNA, which is produced when genes are transcribed. Without these proteins, the speckles [+]

Warbler coloration shaped by evolution via distinct paths (30 Nov 2020) Two genes that are important for the diverse colors and patterns of warbler plumage have evolved through two very different processes, according to a new study. These evolutionary processes could help explain the rapid evolution of these songbirds into so many unique species.

Small molecules control bacterial resistance to antibiotics (30 Nov 2020) Antibiotics have revolutionized medicine by providing effective treatments for infectious diseases such as cholera. But the pathogens that cause disease are increasingly developing resistance to the antibiotics that are most commonly used. Scientists have discovered a molecule that influences the antibiotic-resistance of cholera bacteria.

Scientists discover a motif that guides assembly of the algal pyrenoid (25 Nov 2020) Researchers have discovered that assembly of the algal pyrenoid, a structure that mediates the incorporation of carbon dioxide into sugars, is guided by the presence of a particular protein sequence, or motif.

Novel haplotype-led approach to increase the precision of wheat breeding (25 Nov 2020) Wheat researchers are pioneering a new technique that promises to improve gene discovery for the globally important crop.

Researchers uncover the unique way stem cells protect their chromosome ends (25 Nov 2020) Telomeres are specialized structures at the end of chromosomes which protect our DNA and ensure healthy division of cells. According to a new study, the mechanisms of telomere protection are surprisingly unique in stem cells.

Landmark study generates first genomic atlas for global wheat improvement (25 Nov 2020) In a landmark discovery for global wheat production, a team has sequenced the genomes for 15 wheat varieties representing breeding programs around the world, enabling scientists and breeders to much more quickly identify influential genes for improved yield, pest resistance and other important crop traits.

New wheat and barley genomes will help feed the world (25 Nov 2020) Scientists have unlocked a new genetic variation in wheat and barley - a major boost for the global effort in breeding higher-yielding wheat and barley varieties.

New insights into how the CRISPR immune system evolved (25 Nov 2020) Although CRISPR-Cas has found many uses in biotechnology and medicine, it originates in nature, where it functions as a microbial immune system. Scientists shed new light on how CRISPR-Cas emerged early during the development of life on Earth, as well as how this immune system is constantly adapting to new challenges.

Phytoplankton disturbed by nanoparticles (25 Nov 2020)
Products derived from nanotechnology are efficient and highly sought-after, yet their effects on the environment are still poorly understood. A research team has investigated the effects of nanosilver, currently used in almost 450 products for its antibacterial properties, on the algae known as Poterioochromonas malhamensis. The results show that n [+]

CRISPRi screens reveal sources of metabolic robustness in E. coli (24 Nov 2020)
Metabolic robustness, the ability of a metabolic system to buffer changes in its environment, is not always a welcome feature for microbiologists: it interferes with metabolic engineering or prevents that antibiotics kill bacteria. Therefore it is important to understand the mechanisms that enable metabolic robustness. A massively parallel CRISPRi [+]

Lung-on-chip provides new insight on body's response to early tuberculosis infection (24 Nov 2020) Scientists have developed a lung-on-chip model to study how the body responds to early tuberculosis (TB) infection.

Enzymatic photocaging for the study of gene regulation through DNA methylation (24 Nov 2020) The addition and removal of methyl groups on DNA plays an important role in gene regulation. In order to study these mechanisms more precisely, a team has developed a new method by which specific methylation sites can be blocked and then unblocked at a precise time through irradiation with light (photocaging).

World's first: Drug guides stem cells to desired location, improving their ability to heal (24 Nov 2020) Scientists have created a drug that can lure stem cells to damaged tissue and improve treatment efficacy -- a scientific first and major advance for the field of regenerative medicine.

Researchers reveal switch used in plant defense against animal attack (24 Nov 2020) Researchers have identified the first key biological switch that sounds an alarm in plants when plant-eating animals attack. The mechanism will help unlock a trove of new strategies for improved plant health, from countering crop pest damage to engineering more robust global food webs.

Genetics behind deadly oat blight (23 Nov 2020) A multi-institution team has identified the genetic mechanisms that enable the production of a deadly toxin called Victorin - the causal agent for Victoria blight of oats, a disease that wiped out oat crops in the U.S. in the 1940s.

Making sense of a universe of corn genetics (23 Nov 2020) A new study details the latest efforts to predict traits in corn based on genomics and data analytics. The data management technique could help to 'turbo charge' the seemingly endless amount of genetic stocks contained in the world's seed banks, leading to faster and more efficient development of new crop varieties.

Did early life need long, complex molecules to make cell-like compartments? (23 Nov 2020) Protocell compartments used as models for an important step in the early evolution of life on Earth can be made from short polymers.

Helicates meet Rotaxanes to create promise for future disease treatment (23 Nov 2020) A new approach to treating cancers and other diseases that uses a mechanically interlocked molecule as a 'magic bullet' has been designed.

Proteins in motion (23 Nov 2020) Membrane proteins are more efficient at reaching distal dendrites than soluble proteins.

Coppery titi monkeys do not deceive their partners (23 Nov 2020)
Since methods for genetic paternity analyses were introduced it became clear that many pair-living animal species, including humans, do not take partnership fidelity that seriously. In most species there is some proportion of offspring that is not sired by their social father. Coppery titi monkeys living in the Amazon lowland rainforest seem to be [+]

Folding of SARS-CoV2 genome reveals drug targets -- and preparation for 'SARS-CoV3' (21 Nov 2020)
Researchers report having observed the RNA folding structures of the SARS-CoV2 genome with which the virus controls the infection process. Since these structures are very similar among various beta corona viruses, the scientists not only laid the foundation for the targeted development of novel drugs for treating COVID-19, but also for future occur [+]



Noticias sobre Genética | EL PAÍS


Genética cotidiana (Prof. José Luis Micol Molina) 

Selección de noticias sobre genética aparecida en medios de comunicación español, y se añade un breve comentario. Se incluye un enlace a la noticia en español y cuando es posible, otro al artículo científico original en inglés. (Prof. José Luis Micol Molina, Catedrático de Genética, Universidad Miguel Hernández)


Blog Genes, genomas y otras genialidades (Prof. Ana Aguirre) Universidad del País Vasco

Este blog surge del interés de la autora por la formación de los estudiantes de Grado y de posgrado del ámbito de las Biociencias. Está concebido como un complemento formativo e informativo para estudiantes universitarios y para cualquier persona interesada por conocer de cerca los avances que suceden en el campo de la Genética, de la Biología Molecular y de otras áreas afines. 


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"I'm fascinated by the idea that genetics is digital. A gene is a long sequence of coded letters, like computer information. Modern biology is becoming very much a branch of information technology"
-Richard Dawkins
Contributed by Ilse Alejandra Zepeda Aceves

Genoma: nuestra propia tragicomedia con cuatro únicos personajes, ácidos. El genoma es el teatro que cada uno de nosotros representa y ensaya en una eternidad de ¡bis! Las infinitas funciones de cada una de nuestras células crea el teatro genético de nuestro yo. El ADN es el micro-ordenador de nuestro macro-cerebro infra-utilizado por ser super-desconocido. En este escenario encerramos el Gran Teatro del Mundo y el de nuestra existencia
Fernando Arrabal
Contributed by Maria Hernández Sánchez