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Noticiario genética

            

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Headline (Posted) Abstract
Virus-resistant pigs to vastly improve global animal health (15 Oct 2018) Researchers have successfully produced a litter of pigs that are genetically resistant to Transmissible Gastroenteritis Virus (TGEV), which commonly infects the intestines of pigs and causes almost 100 percent mortality in young pigs.

Unravelling the genetics of fungal fratricide (15 Oct 2018)
Selfish genes are genes that are passed on to the next generation but confer no advantage on the individual as a whole, and may sometimes be harmful. Researchers have, for the first time, sequenced (or charted) two selfish genes in the fungus Neurospora intermedia that cause fungal spores to kill their siblings. Unexpectedly, the genes were not rel [+]


Cellular 'tuning mechanism' builds elegant eyes (15 Oct 2018) Scientists discover a molecular 'brake' that helps control eye lens development in zebrafish.

The tightest non-aminoglycoside ligand for the bacterial ribosomal RNA A-site (15 Oct 2018) A research group has made a significant discovery with positive implications for the development of bacteria-fighting drugs. The aminoacyl-tRNA site (A-site) of the 16S RNA decoding region in the bacterial ribosome looks promising for a new era of antibiotic drug development.

Artificial intelligence aids automatic monitoring of single molecules in cells (15 Oct 2018)
Researchers developed a system that can automatically image single molecules within living cells. This system employs learning via neural networks to focus appropriately on samples, search automatically for cells, image fluorescently labeled single molecules, and track their movements. With this system, the team achieved the automated determination [+]


Cells' route in response to disease is not always straight (15 Oct 2018) The steps cells take in response to challenges are more complex than previously thought, finds new research. The study investigates a system relevant to cancer, viral infection, and diabetes.

An RNA key that unlocks innate immunity (12 Oct 2018) New research shows that a versatile RNA molecule may be a key player in human cells' frontline defenses against viruses.

Getting to the root of lavender's secrets (11 Oct 2018) A team of researchers has identified the complete genetic makeup of the lavender plant, Lavandula angustifolia.

Mouse pups with same-sex parents born in China using stem cells and gene editing (11 Oct 2018)
Researchers were able to produce healthy mice with two mothers that went on to have normal offspring of their own. Mice from two dads were also born but only survived for a couple of days. The work looks at what makes it so challenging for animals of the same sex to produce offspring and suggests that some of these barriers can be overcome using st [+]


Genetic Achilles heel hurts humans fighting hepatitis C (11 Oct 2018) An antimicrobial signaling molecule called interferon lambda 4 has lower activity against the hepatitis C virus in the vast majority of humans compared with chimpanzees and African hunter-gatherer Pygmies, according to a new study.

Researchers modify CRISPR to reorganize genome (11 Oct 2018) Researchers have reworked CRISPR-Cas9 gene-editing technology to manipulate the genome in three-dimensional space, allowing them to ferry genetic snippets to different locations in a cell's nucleus.

New route of acquiring antibiotic resistance in bacteria is the most potent one to date (11 Oct 2018)
For the first time in 60 years, researchers have discovered a new mechanism of genetic transduction, the process by which bacteriophages transfer bacterial DNA between bacteria. This new mechanism (lateral transduction) is the most powerful to date, able to transfer large DNA stretches at high frequencies. It likely plays a major role in bacterial [+]


Scientists accidentally reprogram mature mouse GABA neurons into dopaminergic-like neurons (11 Oct 2018)
Attempting to make dopamine-producing neurons out of glial cells in mouse brains, a group of researchers instead converted mature inhibitory neurons into dopaminergic cells. Their findings reveal that -- contrary to previous belief -- it is possible to reprogram one mature neuron type into another without first reverting it to a stem-cell-like stat [+]


Surfing on calcium waves: A larva's journey to becoming a fly (11 Oct 2018) Researchers have uncovered the neuronal typeset that determines a larva's decision to pupariate, especially when challenged for nutrients. The group has investigated this question in fruit flies to understand how they integrate internal and environmental nutritional cues to make decisions on pupariation.

He's in a rush, she isn't: Reproductive strategy drives slower female aging (11 Oct 2018) The aging of males and females is influenced by how they choose to invest their available energy, according to a study of fruit flies. The results support the idea that differences in strategy between the sexes to maximize the number of offspring contribute to differences in aging between males and females.

Functional salivary gland organoid created (11 Oct 2018) Scientists have, for the first time, succeeded in growing three-dimensional salivary gland tissue that, when implanted into mice, produced saliva like normal glands.

A novel biosensor to advance diverse high-level production of microbial cell factories (11 Oct 2018)
A research group presented a novel biosensor which can produce diverse, high-level microbial cell factories. The biosensor monitors the concentration of products and even intermediates when new strains are being developed. This strategy provides a new platform for manufacturing diverse natural products from renewable resources. The team succeeded i [+]


Nutrients may reduce blood glucose levels (10 Oct 2018) One amino acid, alanine, may produce a short-term lowering of glucose levels by altering energy metabolism in the cell.

Creating custom brains from the ground up (10 Oct 2018) Scientists describe a new way to create customized mouse models for studying the brain. After killing off young brain cells, the developing forebrain can then be reconstituted from genetically engineered stem cells containing the specific genetic modifications desired for study.

How proteins meet on the cell membrane (10 Oct 2018) At last, the researchers have defined the molecular basis of the cell membrane in integrin activation.

Blue roses could be coming soon to a garden near you (10 Oct 2018) For centuries, gardeners have attempted to breed blue roses with no success. But now, thanks to modern biotechnology, the elusive blue rose may finally be attainable. Researchers have found a way to express pigment-producing enzymes from bacteria in the petals of a white rose, tinting the flowers blue.

Why shoals of fish flash silver (10 Oct 2018) Scientists have helped to figure out why shoals of fish flash silver as they twist through the water by studying how the shiny silver cells are created in zebrafish.

A genome under influence (10 Oct 2018)
Researchers recently discovered that 95 percent of our genome seems to be affected by selection and other genetic biases and that markers previously thought to be neutral appear to provide skewed estimates. Their study calls for the re-examination of a plethora of results and provides the tools and recommendations to correct such issues in the futu [+]


Ideal protein to help seniors rebuild lost muscle (09 Oct 2018) While exercise buffs have long used protein supplements to gain muscle, new research suggests one protein source in particular, whey protein, is most effective for seniors struggling to rebuild muscle lost from inactivity associated with illness or long hospital stays.

Scientists go 'back to the future,' create flies with ancient genes to study evolution (09 Oct 2018) Scientists have created fruit flies carrying reconstructed ancient genes to reveal how ancient mutations drove major evolutionary changes in embryonic development--the impact of which we see today.

Cleaning, but safely! Cocoons protect sensitive ant brood during toxic disinfection (09 Oct 2018) Ants are neat: when they move into a new nest box, they spend the first days cleaning it thoroughly. Despite keeping the nest clean, using poison within the nest is dangerous and can kill unprotected brood. However, the silk cocoon that surrounds the ant's sensitive pupae protects them from any harmful effects.

Success is sweet: Researchers unlock the mysteries of the sugarcane genome (09 Oct 2018) For centuries, sugarcane has supplied human societies with alcohol, biofuel, building and weaving materials, and the world's most relied-upon source of sugar. Now, researchers have extracted a sweet scientific prize from sugarcane: Its massive and complex genome sequence, which may lead to the development of hardier and more productive cultivars.

Becoming promiscuous to ensure reproduction (09 Oct 2018) Females of a socially monogamous passerine, the Japanese great tit (Parus minor), become more promiscuous after hatchings fail in the first breeding attempt -- apparently attempting to ensure successful reproduction.

A pheromone-sensing gene that predates land-dwelling vertebrates (09 Oct 2018) Scientists have discovered a gene that appears to play a vital role in pheromone sensing. The gene is conserved across fish and mammals and over 400 million years of vertebrate evolution, indicating that the pheromone sensing system is much more ancient than previously believed.

Genes responsible for difference in flower color of snapdragons identified (08 Oct 2018)
Snapdragons are tall plants, and flower in a range of colors. In Spain, where snapdragons grow wild, these flower colors show a remarkable pattern: areas of magenta and yellow blooming flowers are separated by just a two kilometer long stretch in which flower colors mix. Scientists have investigated the causes of this pattern and identified the gen [+]


Getting a grip on the slow but unique evolution of sharks (08 Oct 2018) Scientists have decoded the whole genomes of two shark species for the first time and improved the whale shark genome sequences released previously. By analyzing the genomes and comparing them with those of other vertebrate species, they have constructed an overview of their unique life histories and evolutionary paths.

There's a better way to decipher DNA's epigenetic code to identify disease (08 Oct 2018) A new method for sequencing the chemical groups attached to the surface of DNA is paving the way for better detection of cancer and other diseases in the blood. These chemical groups mark one of the four DNA 'letters' in the genome, and it is differences in these marks along DNA that control which genes are expressed or silenced.

Expanding fungal diversity, one cell at a time (08 Oct 2018) Researchers have developed a pipeline to generate genomes from single cells of uncultivated fungi. The approach was tested on several uncultivated fungal species representing early diverging fungi, the earliest evolutionary branches in the fungal genealogy that provide a repertoire of important and valuable gene products.

New details of HIV life cycle (05 Oct 2018) The discovery of a small molecule that plays an important part of the HIV life cycle may lead to the development of new treatments for the virus.

Protein dynamics: Molecular machines at work (05 Oct 2018) Researchers have used a special fluorescence-based imaging technique to track the shape changes that occur when pore proteins in the cell membrane export molecules into the extracellular medium.

How malaria infection activates natural killer cells (04 Oct 2018) Malaria-infected red blood cells trigger the immune system's first line of defense by releasing small vesicles that activate a pathogen recognition receptor called MDA5, according to a new study.

Molecular guardians monitor chromosomes during cell division (04 Oct 2018) One of the worst things that can happen to a cell is to end up with the wrong number of chromosomes. This can happen if something goes wrong during cell division, and it can lead to infertility, miscarriages, birth defects, or cancer.

Why huskies have blue eyes (04 Oct 2018) DNA testing of more than 6,000 dogs has revealed that a duplication on canine chromosome 18 is strongly associated with blue eyes in Siberian Huskies.

Common genetic toolkit shapes horns in scarab beetles (04 Oct 2018) Horns have evolved independently multiple times in scarab beetles, but distantly related species have made use of the same genetic toolkit to grow these prominent structures, according to a new study.

'Double agent' in the immune system may make us vulnerable to bacterial infections (04 Oct 2018) Scientists have discovered the role of an immune system double agent. This molecule, called USP18, can help curtail immune responses, but it can also open the door to bacterial infections, such as harmful listeria and staph infections.

 


  

Noticias sobre Genética | EL PAÍS

 

Genética cotidiana (Prof. José Luis Micol Molina) 

 
Selección de noticias sobre genética aparecida en medios de comunicación español, y se añade un breve comentario. Se incluye un enlace a la noticia en español y cuando es posible, otro al artículo científico original en inglés. (Prof. José Luis Micol Molina, Catedrático de Genética, Universidad Miguel Hernández)

 

Blog Genes, genomas y otras genialidades (Prof. Ana Aguirre) Universidad del País Vasco

Este blog surge del interés de la autora por la formación de los estudiantes de Grado y de posgrado del ámbito de las Biociencias. Está concebido como un complemento formativo e informativo para estudiantes universitarios y para cualquier persona interesada por conocer de cerca los avances que suceden en el campo de la Genética, de la Biología Molecular y de otras áreas afines. 

 



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Biological Sciences - Genetics: 394 journals. http://journalseek.net/cgi-bin/journalseek/journalsearch.cgi?field=category&query=bio.genet

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Nuestra capacidad de leer esta secuencia de nuestro genoma tiene todos los ingredientes de una paradoja filosófica. ¿Puede un ser inteligente comprender las instrucciones para hacerse a sí mismo?

John Sulston
Contributed by Amaiur Mendizabal Bengoa