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Headline (Posted) Abstract
Protect forest elephants to conserve ecosystems, not DNA (25 Apr 2018)
New research has found that forest elephant populations across Central Africa are genetically quite similar to one another. Conserving this critically endangered species across its range is crucial to preserving local plant diversity in Central and West African Afrotropical forests -- meaning conservationists could save many species by protecting o [+]


We still don't know how strange celibate animals evolve (25 Apr 2018) A new study has cast doubt on leading theory for how tiny creatures have evolved for 50 million years -- without ever having sex.

Killer whale genetics raise inbreeding questions (24 Apr 2018) A new genetic analysis of Southern Resident killer whales found that two male whales fathered more than half of the calves born since 1990 that scientists have samples from, a sign of inbreeding in the small killer whale population that frequents Washington's Salish Sea and Puget Sound.

Engineered Chinese shrub produces high levels of antimalarial compound (24 Apr 2018)
Artemisinin is a potent antimalarial compound produced naturally in low amounts by the Chinese shrub Artemisia annua, commonly known as sweet wormwood. Researchers in China now report a high-quality draft genome sequence of A. annua and their use of this information along with gene expression data to metabolically engineer plant lines that produce [+]


What can a tasty milkshake teach us about the genetics of heart disease? (24 Apr 2018) Analysis of high-resolution genomic data in a large study population reveals novel low-frequency polymorphisms that drive response to dietary lipids and medication.

A non-coding RNA lasso catches proteins in breast cancer cells (24 Apr 2018) A Danish-German research team has shown that not only the where and when of long non-coding RNA expression is important for their function but also the how. The results can have a big impact on our understanding of dynamic regulation of gene expression in biological processes.

Natural barcodes enable better cell tracking (24 Apr 2018)
Researchers have developed a new genetic analysis technique that harnesses the 10 million small nucleotide polymorphisms (SNPs) found in the human genome as 'barcodes' to create a faster, cheaper, and simpler way to keep track of pooled cells from multiple individuals during multiplexed experiments, enabling large samples of cells from multiple peo [+]


New take on early evolution of photosynthesis (24 Apr 2018) Scientists have begun re-thinking the evolutionary history of photochemical reaction centers (RCs). Their analysis describes a new pathway that ancient organisms may have taken to evolve the great variety of photosynthetic RCs seen today across bacteria, algae, and plants.

The role of 'extra' DNA in cancer evolution and therapy resistance (23 Apr 2018)
Researchers tracked genomic alterations detected in patient samples during tumor cell evolution in culture, in patient-derived xenograft (PDX) mouse models from the cultures, as well as before and after treatment in patients. The team reports that tumor progression was often driven by cancer-promoting genes, known as oncogenes, on extrachromosomal [+]


Found: A new form of DNA in our cells (23 Apr 2018) In a world first, researchers have identified a new DNA structure -- called the i-motif -- inside cells. A twisted 'knot' of DNA, the i-motif has never before been directly seen inside living cells.

Complete skin regeneration system of fish unraveled (23 Apr 2018) Researchers have succeeded in observing the behavior of epidermal cells for the regeneration of smooth skin without remaining scar tissue using their model animal, the zebrafish.

Endangered salamander offers clues on healing spinal cord injury (23 Apr 2018) A new study takes a comparative approach to pinpoint what happens differently in humans versus other animals to explain why they can successfully regenerate neurons while we instead form scar tissue. By learning from the similarities and differences, researchers hope to find new leads in the treatment of spinal cord injury.

Eating more fish could prevent Parkinson's disease (23 Apr 2018) Parvalbumin, a protein found in great quantities in several different fish species, has been shown to help prevent the formation of certain protein structures closely associated with Parkinson's disease. A new study shines more light on the link between consumption of fish and better long-term neurological health.

Scientists discover gene controlling genetic recombination rates (21 Apr 2018) Genetic recombination is vital to natural selection, yet some species display far more crossover than others. Scientists have discovered a gene in fruit flies that is responsible for the evolution of these recombination rates.

Fungus: The good, the bad and their fortuitous differences (20 Apr 2018) Genetic differences between two very similar fungi, one that led to Quorn™, the proprietary meat substitute, and another that ranks among the world's most damaging crop pathogens, have exposed the significant features that dictate the pair's very different lifestyles, features that promise targets for controlling disease.

Fat cells seem to remember unhealthy diet (20 Apr 2018) Fat cells can be damaged in a short amount of time when they are exposed to the fatty acid palmitate or the hormone TNF-alpha through a fatty diet, a new study shows. The researchers hope this new knowledge may be used to develop new preventive strategies for diabetes.

Wood formation model to fuel progress in bioenergy, paper, new applications (20 Apr 2018) Need stronger timber, better biofuels or new sources of green chemicals? A systems biology model developed over decades of research will accelerate progress in engineering trees for specific needs.

A complete cell atlas and lineage tree of the immortal flatworm (19 Apr 2018) From one stem cell to many differentiated body cells: Scientists have now published a comprehensive lineage tree of a whole adult animal. This was made possible by a combination of RNA and computational technologies.

Great Barrier Reef coral predicted to last at least 100 years before extinction from climate change (19 Apr 2018) A common Great Barrier Reef coral species has enough genetic diversity to survive at least 100 years before succumbing to global warming, researchers predict.

Ramped up fight-or-flight response points to history of warfare for humans and chimps (19 Apr 2018) Humans and chimpanzees recently evolved a more active fight-or-flight response compared to other primates, possibly in response to the threat of warfare.

Gene-edited stem cells show promise against HIV in non-human primates (19 Apr 2018) Gene editing of bone marrow stem cells in pigtail macaques infected with simian/human immunodeficiency virus (SHIV) significantly reduces the size of dormant 'viral reservoirs' that pose a risk of reactivation.

Genome Jenga study reveals unexpected gene alliances in the cell (19 Apr 2018) The largest study of its kind sheds light on how genes work together to keep cells healthy, paving the way for predicting a person's risk of disease.

Dogs could be more similar to humans than we thought (19 Apr 2018) Dog and human gut microbiomes have more similar genes and responses to diet than we previously thought, according to a new study

Study predicts 2018 flu vaccine will likely have 20 percent efficacy (19 Apr 2018) A new study of 6,610 human flu sequences predicts that this fall's flu vaccine will likely have the same reduced efficacy against the dominant circulating strain of influenza A as the vaccine given in 2016 and 2017 due to viral mutations related to vaccine production in eggs.

Far-red fluorescent silk can kill harmful bacteria as biomedical and environmental remedy (19 Apr 2018) A silk hybrid material attacks bacteria when illuminated by a green light, thanks to a far-red fluorescent protein researchers transferred to its genetic makeup.

Unique protein is a vulnerability in the malaria parasite (18 Apr 2018) The malaria parasite is highly dependent on a unique protein for infecting new mosquitoes. This protein could be a target for the development of new drugs.

Evolution: Urban life leaves behind traces in the genome of bumblebees (18 Apr 2018) Bumblebees living in the city have genes that differ from their relatives in the countryside. Although genetic differences are minor, they may influence how well the insects adapt to their habitat. These differences in genetic makeup are an indication that urban life does impact the evolutionary trajectory of a species, write researchers.

First gene drive targeting worldwide crop pest (17 Apr 2018) Biologists have created the world's first gene drive system -- a mechanism for manipulating genetic inheritance -- in Drosophila suzukii, an agricultural pest that has invaded much of the United States and caused millions of dollars in damage to high-value berry and other fruit crops.

Solving the structure of ATP synthase (17 Apr 2018) Scientists have solved the structure of mitochondrial ATP synthase, an enzyme that makes ATP, adenosine triphosphate, the major energy source of cells.

Machine learning techniques may reveal cause-effect relationships in protein dynamics data (17 Apr 2018)
Machine learning algorithms excel at finding complex patterns within big data, so researchers often use them to make predictions. Researchers are pushing the technology beyond finding correlations to help uncover hidden cause-effect relationships and drive scientific discoveries. Researchers are integrating machine learning techniques into their wo [+]


Bacterial 'gene swapping' sparks disease outbreaks (17 Apr 2018) A new study documents how the ability of bacteria to swap genetic material with each other can directly affect the emergence and spread of globally important infectious diseases.

How does plant DNA avoid the ravages of UV radiation? (17 Apr 2018)
Plants can't come in from the sun or slather on sunblock; instead they have a super robust DNA repair kit to combat UV radiation. Today, the lab of 2015 Nobel laureate Aziz Sancar published the first repair map of an entire multicellular organism to show how the 'nucleotide excision repair' system works much more efficiently in the active genes of [+]


'Mono' virus linked to seven serious diseases (16 Apr 2018)
The Epstein-Barr virus (EBV) -- best known for causing mononucleosis -- also increases the risks for some people of developing seven other major diseases, according to a new study. The diseases are: systemic lupus erythematosus, multiple sclerosis, rheumatoid arthritis, juvenile idiopathic arthritis, inflammatory bowel disease, celiac disease, and [+]


Timing is everything: Researchers describe genetic clockwork in germ cell development (16 Apr 2018)
The nematode C. elegans is truly an organizational talent: The tiny animals live for only two to three weeks, with sexual maturity lasting only four days. They still manage to generate over 300 offspring during this period. For this ambitious development program to function optimally, a large number of processes must be synchronized within their ce [+]


Breakthrough brings gene-editing medicine one step closer to patient applications (13 Apr 2018) Researchers have discovered a way to greatly improve the accuracy of gene-editing technology by replacing the natural guide molecule it uses with a synthetic one called a bridged nucleic acid, or BNA. The research promises to bring the technology much closer to therapeutic reality.

Chemistry: Observing biological nanotransporters (13 Apr 2018) A research team was able to describe with atomic detail how molecules are transported through biological membranes. Computer simulations and spectroscopic experiments provided insights into the work of so-called ABC transporters. These proteins play an important role in the drug resistance of tumor cells and bacteria.

'Scaffolding' method allows biochemists to see proteins in remarkable detail (13 Apr 2018) Biochemists have achieved a major goal in biology: seeing at near atomic detail the smallest protein ever visualized by the technique whose development won the 2017 Nobel Prize in chemistry. Until now, this method has not worked with the small proteins inside cells.

How molecules in cells 'find' one another and organize into structures (12 Apr 2018) A longstanding mystery in biology is how the millions of molecules bumping around in a cell "find" one another and organize into functional structures. So it was a big surprise in 2008 when a group realized that simple phase separations -- like oil separating from water -- may be one important way to create order inside a cell.

Sweet potato history casts doubt on early contact between Polynesia and the Americas (12 Apr 2018) New evidence shows that sweet potatoes arose before there were any humans around to eat them. The findings also suggest that the sweet potato crossed the ocean from America to Polynesia without any help from people. The discovery raises doubts about the existence of pre-Columbian contacts between Polynesia and the American continent.

Ebola: Overestimated mutation rate (12 Apr 2018) At the start of the epidemic in West Africa, the Ebola virus did not change as rapidly as thought at the time. Researchers explain why scientists misjudged it at the time.

 


  

Noticias sobre Genética | EL PAÍS

 

Genética cotidiana (Prof. José Luis Micol Molina) 

 
Selección de noticias sobre genética aparecida en medios de comunicación español, y se añade un breve comentario. Se incluye un enlace a la noticia en español y cuando es posible, otro al artículo científico original en inglés. (Prof. José Luis Micol Molina, Catedrático de Genética, Universidad Miguel Hernández)

 

Blog Genes, genomas y otras genialidades (Prof. Ana Aguirre) Universidad del País Vasco

Este blog surge del interés de la autora por la formación de los estudiantes de Grado y de posgrado del ámbito de las Biociencias. Está concebido como un complemento formativo e informativo para estudiantes universitarios y para cualquier persona interesada por conocer de cerca los avances que suceden en el campo de la Genética, de la Biología Molecular y de otras áreas afines. 

 



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Curso de Genética - Grado Genética de la UAB
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Prof. Antonio Barbadilla

 

 

 

 

Biological Sciences - Genetics: 394 journals. http://journalseek.net/cgi-bin/journalseek/journalsearch.cgi?field=category&query=bio.genet

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Nuestra capacidad de leer esta secuencia de nuestro genoma tiene todos los ingredientes de una paradoja filosófica. ¿Puede un ser inteligente comprender las instrucciones para hacerse a sí mismo?

John Sulston
Contributed by Amaiur Mendizabal Bengoa