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Noticiario genética


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Headline (Posted) Abstract
Bearded dragon embryos become females either through sex chromosomes or hot temperatures (15 Apr 2021) Bearded dragon embryos can use two different sets of genes to become a female lizard -- one activated by the sex chromosomes and the other activated by high temperatures during development, researchers report.

The architect of genome folding (15 Apr 2021)
The DNA molecule is not naked in the nucleus. Instead, it is folded in a very organized way by the help of different proteins to establish a unique spatial organization of the genetic information. This 3D spatial genome organization is fundamental for the regulation of our genes and has to be established de novo by each individual during early embr [+]

RNA holds the reins in bacteria: Researchers observe RNA controlling protein synthesis (14 Apr 2021) To better understand how RNA in bacteria gives rise to protein -- and potentially target these processes in the design of new antibiotics -- researchers are turning their attention to the unique way this process happens in bacteria. Researchers have directly observed previously hidden RNA regulatory mechanisms within bacteria.

The chillest ape: How humans evolved a super-high cooling capacity (14 Apr 2021)
Researchers have discovered how a uniquely high density of sweat glands evolved in the human genome. Researchers showed that the higher density of sweat glands in humans is due mostly to accumulated changes in a regulatory region of DNA -- called an enhancer region -- that drives the expression of a sweat gland-building gene, explaining why humans [+]

Inside the protein channel that keeps bacteria alive (13 Apr 2021) A novel method for studying how one crucial membrane protein functions may pave the way for a new kind of broad-spectrum antibiotic.

Aging signatures across diverse tissue cells in mice (13 Apr 2021) Researchers have identified molecular signatures of the aging process in mice.

Amoeba biology reveals potential treatment target for lung disease (13 Apr 2021) In a series of experiments that began with amoebas -- single-celled organisms that extend podlike appendages to move around -- scientists say they have identified a genetic pathway that could be activated to help sweep out mucus from the lungs of people with chronic obstructive pulmonary disease a widespread lung ailment.

Molecular assembly line to design, test drug compounds streamlined (13 Apr 2021) Researchers have fine-tuned the molecular assembly line that creates antibiotics via engineered biosynthesis.

Genetic predisposition to schizophrenia may increase risk of psychosis from cannabis use (13 Apr 2021) New research shows that while cannabis users had higher rates of psychotic experiences than non-users across the board, the difference was especially pronounced among those with high genetic predisposition to schizophrenia.

Simple genetic modification aims to stop mosquitoes spreading malaria (13 Apr 2021) Altering a mosquito's gut genes to make them spread antimalarial genes to the next generation of their species shows promise as an approach to curb malaria.

A novel, quick, and easy system for genetic analysis of SARS-CoV-2 (13 Apr 2021)
Researchers established a novel PCR-based, bacterium-free reverse genetics system for SARS-CoV-2 using the CPER method, which is simpler and faster than previous methods. Large numbers of recombinant SARS-CoV-2 can be produced in about two weeks. This method can be used to modify the viral genome, allowing detailed study of the functions of mutatio [+]

Frog species with 6 sex chromosomes offer new clues on evolution of complex XY systems (13 Apr 2021) The O. swinhoana frog species is the first vertebrate known to retain descendant genes that now determine sex in mammals, birds, and fishes inherited from a common ancestor.

Researchers engineer probiotic yeast to produce beta-carotene (12 Apr 2021) Researchers have genetically engineered a probiotic yeast to produce beta-carotene in the guts of laboratory mice. The advance demonstrates the utility of work the researchers have done to detail how a suite of genetic engineering tools can be used to modify the yeast.

A multidimensional view of the coronavirus (12 Apr 2021) What exactly happens when the coronavirus SARS-CoV-2 infects a cell? New research paints a comprehensive picture of the viral infection process.

For tomato genes, one plus one doesn't always make two (12 Apr 2021) Millions of small genetic variations make it hard to predict how a particular targeted mutation will affect desirable crop traits. Scientists have now deciphered the relationships between dozens of mutations in tomatoes, a major advance towards more efficient genome-editing in crops.

Technique allows mapping of epigenetic information in single cells at scale (12 Apr 2021)
Histones are tiny proteins that bind to DNA and hold information that can help turn on or off individual genes. Researchers have developed a technique that makes it possible to examine how different versions of histones bind to the genome in tens of thousands of individual cells simultaneously. The technique was applied to the mouse brain and can b [+]

Pain receptors linked to the generation of energy-burning brown fat cells (12 Apr 2021) A new source of energy expending brown fat cells has been uncovered by researchers, which they say points towards potential new therapeutic options for obesity.

Speeding up sequence alignment across the tree of life (12 Apr 2021) A team of researchers develops new search capabilities that will allow to compare the biochemical makeup of different species from across the tree of life.

Auxin visualized for the first time (12 Apr 2021) A biosensor visualizes redistribution dynamics of the plant hormone auxin in living cells.

Metabolic changes in fat tissue in obesity associated with adverse health effects (09 Apr 2021)
A twin study indicates that the machinery responsible for energy handling in fat tissue is working poorly in obesity. In the study, a clear reduction was seen in the activity of mitochondrial genes in obesity in fat tissue, while similar genome-level change in muscle mitochondria was minor. A link with adverse health effects was identified in the m [+]

Scientists discover 'jumping' genes that can protect against blood cancers (08 Apr 2021) New research has uncovered a surprising role for so-called 'jumping' genes that are a source of genetic mutations responsible for a number of human diseases. Scientists made the unexpected discovery that these DNA sequences, also known as transposons, can protect against certain blood cancers.

Green chemistry and biofuel: The mechanism of a key photoenzyme decrypted (08 Apr 2021) Scientists have decrypted the functioning of the enzyme FAP, useful for producing biofuels and for green chemistry.

The tuberculosis pathogen releases its toxin by a novel protein transport system (08 Apr 2021)
Six years ago, researchers described the first toxin ever found for the deadly pathogen Mycobacterium tuberculosis. However, the mechanism for its secretion from the bacterium was unknown. Now, researchers describe two small Esx proteins that form pores in bacterial membranes and are essential for toxin release. This transport system may be widespr [+]

Living fossils: Microbe discovered in evolutionary stasis for millions of years (08 Apr 2021) Research has revealed that a group of microbes found deep underground in three continents have been at an evolutionary standstill for millions of years. The discovery could have significant implications for biotechnology applications and scientific understanding of microbial evolution.

How to tame a restless genome (08 Apr 2021) LTR retrotransposons are small stretches of DNA that can move around the genome. Researchers figured out how cells keep these 'jumping genes' anchored, preventing them from landing in the wrong place.

PNA-based technique an essential part of the gene editing toolkit (07 Apr 2021) A peptide nucleic acid-based gene editing technique is an essential part of the gene editing toolkit in addition to CRISPR-Cas systems.

New biosensor makes control hormone auxin visible in cells (07 Apr 2021) The hormone auxin is of central importance for the development of plants. Scientists have now developed a novel sensor that makes the spatial distribution of auxin in the cells of living plants visible in real time. The sensor opens up completely new insights into the inner workings of plants for researchers.

Genome sequencing reveals a new species of bumblebee (07 Apr 2021) While studying genetic diversity in bumblebees in the Rocky Mountains, USA, researchers discovered a new species. They named it Bombus incognitus.

Junctions between three cells serve as gateways for the transport of substances (07 Apr 2021) Developmental biologists have discovered that during egg development in fruit flies, intercellular gaps open between epithelial cells in a controlled way at the points where three cells meet. This process allows yolk proteins to be transported into the egg cell.

The incredible bacterial 'homing missiles' that scientists want to harness (07 Apr 2021)
Imagine there are arrows that are lethal when fired on your enemies yet harmless if they fall on your friends. It's easy to see how these would be an amazing advantage in warfare, if they were real. Well, something just like these arrows does indeed exist, and they are used in warfare ... just on a different scale. These weapons are called tailocin [+]

A novel form of cellular logistics (06 Apr 2021) Biophysicists have shown that a phenomenon known as diffusiophoresis, which can lead to a directed particle transport, can occur in biological systems.

Scientists reveal elusive inner workings of antioxidant enzyme with therapeutic potential (06 Apr 2021)
The enzyme manganese superoxide dismutase (MnSOD) plays a critical role in maintaining human health by keeping the amount of harmful reactive oxygen molecules in cells under control. By using neutron scattering, researchers have now obtained a complete atomic portrait of the enzyme, revealing key information about its catalytic mechanism. The work [+]

How the fly selects its reproductive male (06 Apr 2021)
A team has discovered an RNA coding for a micro-peptide - a very small protein - that plays a crucial role in the competition between spermatozoa from different males of the Drosophila with which the female mates. In addition to shedding new light on this biological mechanism, this work highlights the importance of small peptides, a class of protei [+]

Radical attack on live cells (06 Apr 2021)
Is there a way to chemically manipulate small, confined areas on cellular surfaces? Scientists have developed a microfluidic probe to send a flow of free radicals on live cells and track the outcome using fluorescence imaging. This approach makes it possible for the first time to generate a reaction zone of free radicals with controlled size and co [+]

Source of Zika neurodevelopmental defects (06 Apr 2021) A study identified how microcephaly (abnormally small heads) and blindness may develop in Zika-infected fetuses, as well as a new way to potentially prevent these neurodevelopmental defects.

Glass nanopore pulls DNA like spaghetti through a needle (06 Apr 2021) Nanopore sensing can extract cell-free DNA from a liquid sample. Researchers used electric current to direct free-floating DNA into the 20 nanometer opening of a glass tube. The DNA concentrated near the surface, making it relatively easy to collect numerous samples.

Origins of life could have started with DNA-like XNAs (06 Apr 2021) Experiments show how molecules that might have existed in early Earth can come together, with the potential to form DNA precursors.

Discovery is key to creating heat-tolerant crops (06 Apr 2021) By 2050, global warming could reduce crop yields by one-third. To modify plants' response to heat, scientists must first understand how plants sense temperature. Researchers have discovered a gene that's key to this process.

New method expands the world of small RNAs (05 Apr 2021) Biomedical scientists have developed a new RNA-sequencing method -- 'Panoramic RNA Display by Overcoming RNA Modification Aborted Sequencing,' or PANDORA-seq -- that can help discover numerous modified small RNAs that were previously undetectable.

An artful study of cellular development in leaves (05 Apr 2021) Researchers tracked 20,000 cells to find out what made each one unique and to learn how the cells coordinate to build a leaf. Collaboration with a visual artist added additional dimensions to the work.



Noticias sobre Genética | EL PAÍS


Genética cotidiana (Prof. José Luis Micol Molina) 

Selección de noticias sobre genética aparecida en medios de comunicación español, y se añade un breve comentario. Se incluye un enlace a la noticia en español y cuando es posible, otro al artículo científico original en inglés. (Prof. José Luis Micol Molina, Catedrático de Genética, Universidad Miguel Hernández)


Blog Genes, genomas y otras genialidades (Prof. Ana Aguirre) Universidad del País Vasco

Este blog surge del interés de la autora por la formación de los estudiantes de Grado y de posgrado del ámbito de las Biociencias. Está concebido como un complemento formativo e informativo para estudiantes universitarios y para cualquier persona interesada por conocer de cerca los avances que suceden en el campo de la Genética, de la Biología Molecular y de otras áreas afines. 


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