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Headline (Posted) Abstract
Quality control is vital for the energy production of cells (11 Dec 2017) Researchers have uncovered a mitochondrial error-correction mechanism, which is vital for the construction of the mitochondrial respiratory chain and the energy production of cells.

How Zika virus induces congenital microcephaly (11 Dec 2017)
Epidemiological studies show that in utero fetal infection with the Zika virus (ZIKV) may lead to microcephaly, an irreversible congenital malformation of the brain characterized by an incomplete development of the cerebral cortex. However, the mechanism of Zika virus-associated microcephaly remains unclear. Scientists have now identified a specifi [+]


Yeast can be engineered to create protein pharmaceuticals (11 Dec 2017) It took several years, but a research team has finally succeeded in mapping out the complex metabolism of yeast cells. The breakthrough means a huge step forward in the potential to more efficiently produce protein therapies for diseases such as cancer.

Scientists channel graphene to understand filtration, ion transport into cells (08 Dec 2017) Nanometer-scale pores etched into layers of graphene can provide a simple model for the complex operation of ion channels, researchers have demonstrated.

Acrobatic duo in the cells (08 Dec 2017) Just like an acrobatic duo, some proteins lend each other stability. Researchers have discovered that the protein 'Trigger factor' recognizes a partner by unstable, flexible domains, to then together form a stable protein duo.

Suite of papers shed light on decade-long stem cell mystery (07 Dec 2017) A series of studies has shed light on vital, yet previously unclear, aspects of cell reprogramming.

Algae could feed and fuel planet with aid of new high-tech tool (07 Dec 2017) Vast quantities of medicines and renewable fuels could be produced by algae using a new gene-editing technique, a study suggests.

CRISPR-Cas9 technique targeting epigenetics reverses disease in mice (07 Dec 2017) Scientists report a modified CRISPR-Cas9 technique that alters the activity, rather than the underlying sequence, of disease-associated genes. The researchers demonstrate that this technique can be used in mice to treat several different diseases.

The unique pentraxin-carbonic anhydrase protein regulates the ability of fish to swim (07 Dec 2017) A study has shown that carbonic anhydrase VI (CA VI) is present in some species as a combination of two proteins.

A spring-loaded sensor for cholesterol in cells (07 Dec 2017) New research explains how an enzyme acts as a kind of thermostat that responds to and adjusts levels of cholesterol in the cell. This insight could lead to new strategies for combating high cholesterol.

The world's smallest Mona Lisa (06 Dec 2017) New techniques in DNA self-assembly allow researchers to create the largest to-date customizable patterns with nanometer precision on a budget.

Invasive 'supervillain' crab can eat through its gills (06 Dec 2017) Invasive green shore crabs can 'eat' by absorbing nutrients across its gills -- the first demonstration of this ability in crustaceans -- scientists have found.

Bioelectronic 'nose' can detect food spoilage by sensing the smell of death (06 Dec 2017) Strong odors are an indicator that food has gone bad, but there could soon be a new way to sniff foul smells earlier on. As reported in ACS Nano, researchers have developed a bioelectronic

Cell tissue must not freeze! (06 Dec 2017)
Nature has evolved sugars, amino acids, and special antifreeze proteins as cryoprotectants. People use organic solvents and synthetic polymers as additives to prevent cell cultures from freezing damage. Now, scientists have combined both methods: They introduced polyproline, a polypeptide made of the natural amino acid proline, as an effective cryo [+]


Viruses share genes with organisms across the tree of life, study finds (06 Dec 2017) A new study finds that viruses share some genes exclusively with cells that are not their hosts. The study adds to the evidence that viruses swap genes with a variety of cellular organisms and are agents of diversity, researchers say.

How ribosomes shape the proteome (06 Dec 2017)
Cells are crowded with macromolecules, which limits the diffusion of proteins, especially in prokaryotic cells without active transport in the cytoplasm. While investigating the relationship between crowding, ionic strength and protein diffusion, biochemists made a fascinating discovery: positively charged proteins stick to the surface of ribosome [+]


First DNA sequence from a single mitochondria (06 Dec 2017) DNA sequences between mitochondria within a single cell are vastly different, researchers found. This knowledge will help to better illuminate the underlying mechanisms of many disorders that start with accumulated mutations in individual mitochondria and provide clues about how patients might respond to specific therapies.

Dahl's toad-headed turtle threatened by fragmented habitat, shrinking populations (05 Dec 2017) A recent study shows that the Dahl's Toad-headed Turtle (Mesoclemmys dahli), a rare reptile found only in Colombia, is threatened with extinction due to alarmingly small and fragmented populations and high levels of inbreeding.

Living cell membranes can self-sort their components by 'demixing' (05 Dec 2017) Scientists show for the first time that the complex distribution of molecules within a membrane of a living yeast cell arises through demixing.

Scientists explain Rudolph, Grinch, Scrooge (05 Dec 2017) A reindeer with a red glowing nose. A heart, two sizes two small, that suddenly grows three sizes. A trip to the past and to the future — all in one night. Researchers dug deep into their reserves of scientific expertise to explain how these inexplicable plot lines in holiday classics just might be (almost) possible.

Protein-folding simulations sped up (05 Dec 2017)
Proteins are huge molecules whose function depends on how they fold into intricate structures. To understand how these molecules work, researchers use computer modeling to calculate how proteins fold. Now, a new algorithm can accelerate those vital simulations, enabling them to model phenomena that were previously out of reach. The results can even [+]


New process could be key to understanding complex rearrangements in genome (05 Dec 2017) Biologists have successfully harnessed new technology to develop an approach that could allow for rapid and precise identification of the CGRs involved in disease, cancer and disorder development, which is critical for diagnosis and treatment.

Possible new way to treat parasitic infections discovered (05 Dec 2017) A chemical that suppresses the lethal form of a parasitic infection caused by roundworms that affects up to 100 million people and usually causes only mild symptoms has now been identified by researchers.

Which sequences make DNA unwrap and breathe? (05 Dec 2017)
Accessing DNA wrapped into basic units of packaging depends on the underlying sequence of the building blocks. Like Christmas presents, some nucleosomes are easier to unwrap than others before genes are expressed. Scientists now demonstrate the role of the DNA sequence in making it possible for packaged DNA to open up and allow genes to be read and [+]


Six genes driving peanut allergy reactions identified (05 Dec 2017)
Six genes that activate hundreds of other genes in children experiencing severe allergic reactions to peanuts have now been identified by researchers. This is the first study in human trials to identify genes driving acute peanut allergic reactions using a double-blind placebo-controlled approach with comprehensive sequencing of genes expressed bef [+]


Polyunsaturated fatty acids linked to reduced allergy risk (05 Dec 2017) High levels of polyunsaturated fatty acids in children’s blood are associated with a reduced risk of asthma or rhinitis at the age of 16 years, new research shows.

Shining a light on plant growth and development (05 Dec 2017) Researchers have identified the portion of a plant photoreceptor responsible for light-dependent changes in gene expression.

How cells rebuild after mitosis (04 Dec 2017) New research has revealed how cells rebuild their nucleus and organize their genome when they divide, a discovery which could have major implications for understanding cancer and degeneration.

Computerized biology, or how to control a population of cells with a computer (04 Dec 2017)
Researchers explain computer control of cellular processes. Hybrid experimental platforms combining microscopes and software are enabling researchers to interface living cells with control algorithms in real time. The research illustrates that these solutions make it possible to create new and easily reprogrammable behaviors of cell populations. Th [+]


Genes identified that distinguish mammals from other animals (04 Dec 2017)
What distinguishes Homo sapiens from other living beings? And the group of mammals? What makes them different? Researchers analysed the already-sequenced genomes of 68 mammals and identified 6,000 families of genes that are only found in these animals. These are genes with no homologues outside mammals, in other words, they are not present in other [+]


Discovery of a mechanism for determining the direction of collective cell migration (04 Dec 2017) The phenomenon of collective cell migration has been observed in the process of animal development, the healing of wounds, and cancer cell invasion. Researcher have found that when the activity of a molecule called ERK MAP kinase is propagated to neighboring cells, the cells migrate in the opposite direction of ERK propagation.

The function of many proteins remains uncertain: Blind spots on protein maps quantified (04 Dec 2017)
While researchers already know what the DNA-blueprints look like for most proteins, they do not know what many of these proteins actually do in the body. An interdisciplinary team composed of experimental and computational scientists has now systematically quantified and characterized the extent of this knowledge gap. An unprecedented effort has be [+]


Surprise in the kangaroo family tree (04 Dec 2017)
Ironically, it is jumping genes that indicate the need for a reorganization of the kangaroos' phylogenetic tree. According to a new study, the swamp wallaby is more closely related to the remaining wallaby species and the large red and grey kangaroos and wallaroos than previously assumed. This study was the first to examine the relationships within [+]


How saturated fatty acids damage cells (01 Dec 2017) Researchers have developed a new microscopy technique that allows for the direct tracking of fatty acids after they've been absorbed into living cells. What they found using this technique could have significant impact on both the understanding and treatment of obesity, diabetes and cardiovascular disease.

Bottle gourd genome provides insight on evolutionary history, relationships of cucurbits (01 Dec 2017) Researchers have produced the first high-quality genome sequence for the bottle gourd (Lagenaria siceraria) and a reconstructed genome of the most recent Cucurbitaceae ancestor.

Drought-resistant plant genes could accelerate evolution of water-use efficient crops (01 Dec 2017) Scientists have identified a common set of genes that enable different drought-resistant plants to survive in semi-arid conditions, which could play a significant role in bioengineering and creating energy crops that are tolerant to water deficits.

Chick embryos provide valuable genetic data for understanding human development (01 Dec 2017)
An international collaboration of researchers from Japan, Russia, Spain, and Australia has created the first genome-wide set of avian transcription start sites. Their data have been made available through the web-based, open-access, interactive DNA visualization system. The database and their CAGE-based TSS mapping method are expected to greatly fa [+]


Bat cave study sheds new light on origin of SARS virus (30 Nov 2017) Genetic recombination between viral strains in bats may have produced the direct evolutionary ancestor of the strain that caused a deadly outbreak of severe acute respiratory syndrome (SARS) in humans, according to new research.

To proliferate or not to proliferate? A cellular spring replies (30 Nov 2017)
The epithelium is subjected to multiple types of mechanical stretch. Researchers have discovered that the proteins ZO-1 and ZO-2, which contribute to the tightness of the epithelium, perceive these physical signals and activate cellular responses accordingly. These results reveal a novel process by which mechanical forces can regulate the structure [+]


Interrupted reprogramming converts adult cells into high yields of progenitor-like cells (30 Nov 2017)
A modified version of iPS methodology, called interrupted reprogramming, allows for a highly controlled, safer, and more cost-effective strategy for generating progenitor-like cells from adult cells. Researchers converted adult mouse respiratory tract cells called Club cells into large, pure populations of induced progenitor-like cells, which retai [+]


 


  

Noticias sobre Genética | EL PAÍS

 

Genética cotidiana (Prof. José Luis Micol Molina) 

 
Selección de noticias sobre genética aparecida en medios de comunicación español, y se añade un breve comentario. Se incluye un enlace a la noticia en español y cuando es posible, otro al artículo científico original en inglés. (Prof. José Luis Micol Molina, Catedrático de Genética, Universidad Miguel Hernández)

 

Blog Genes, genomas y otras genialidades (Prof. Ana Aguirre) Universidad del País Vasco

Este blog surge del interés de la autora por la formación de los estudiantes de Grado y de posgrado del ámbito de las Biociencias. Está concebido como un complemento formativo e informativo para estudiantes universitarios y para cualquier persona interesada por conocer de cerca los avances que suceden en el campo de la Genética, de la Biología Molecular y de otras áreas afines. 

 



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